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Search Results for " high-throughput screening "

7

Compounds

Cat No. Product Name Synonyms Targets
T11344 G150 DNA , cGAS
G150 inhibited interferon expression triggered by DSDNA with IC50 of 10.2 nM.G150 is an effective and highly selective inhibitor of human cyclic GMP-AMP synthase (H-CGAS).
T4531 GSK2200150A Antibacterial
GSK2200150A is an anti-tuberculosis (TB) agent identified by high-throughput screening (HTS) campaign.
T3313 D-Luciferin Firefly luciferin,D-(-)-Luciferin Others
D-Luciferin (D-(-)-Luciferin) is a popular bioluminescent substrate of luciferase in the presence of ATP, used in luciferase-based bioluminescence imaging and cell-based high-throughput screening applications.
T4062 CAY10602 Sirtuin
CAY10602 is a SIRT1 activator. CAY10602 was derived from high throughput screening for compounds that increase SIRT1-mediated deacetylation of a SIRT1-specific substrate. Functional assays show that CAY10602 dose-depende...
T83800 6-Biotin-17-NAD+ sodium 6-Biotin-17-Nicotinamide adenine dinucleotide,β-Nicotinamide-N6-(2-(6-(6-[biotinyl]aminohexanoyl)aminohexanoyl)aminoethyl)adenine dinucleotide
6-Biotin-17-NAD+, a biotinylated derivative of the signaling molecule and enzyme cofactor NAD+, is utilized in high-throughput screening (HTS) assays to measure the activity of mitochondrial complex I, also referred to a...
T37062 L-Leucine-7-amido-4-methylcoumarin hydrochloride
L-Leu-AMC is a fluorogenic substrate for leucine aminopeptidase.1Upon enzymatic cleavage by leucine aminopeptidase, AMC is released and its fluorescence can be used to quantify leucine aminopeptidase activity. AMC displa...
T83952 CoraFluor 1, amine reactive
CoraFluor 1, an amine-reactive terbium-based compound, serves as a potent donor in time-resolved Förster resonance energy transfer (TR-FRET) assays, including applications in target engagement and ternary complex assessm...
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